
Заранее спасибо
Модератор: Владислав
...Topical application of gamma-linolenic acid to the testosterone-treated flank organ suppressed this testosterone effect. ...
...Androgen action in many organs, such as prostate and skin, is dependent on the conversion of testosterone by 5 alpha-reductase to 5 alpha-dihydrotestosterone. 5 alpha-Dihydrotestosterone then binds to the androgen receptor to regulate specific gene expression. Inhibitors of 5 alpha-reductase are useful for the selective treatment of prostatic cancer, benign prostate hyperplasia, acne, baldness and female hirsutism, without affecting spermatogenesis, sexual behavior and smooth muscle growth, that do not require the conversion of testosterone to 5 alpha-dihydrotestosterone. Certain unsaturated fatty acids, such as gamma-linolenic acid, are potent 5 alpha-reductase inhibitors, suggesting a linkage between unsaturated fatty acids and androgen action. Mutations in androgen receptor genes are responsible for many cases of androgen-insensitivity. In some prostate cancer cells, some antiandrogens may act like androgens in stimulating the proliferation of the cancer cells because these antiandrogens can bind to a mutated androgen receptor and transactivate target genes. Prostate cancers are usually androgen-dependent initially but can lose dependency and responsiveness. Tumor cells which are resistant to endocrine therapy ultimately proliferate. Androgen-independent or androgen-repressive cells can arise from androgen-sensitive prostate cancer cells by changes in specific gene expression over time in a clonal isolate. This change in androgen responsiveness was accompanied by a change in androgen receptor expression and transcriptional activity as well as expression of some oncogenes. ...
http://volosy.com/forum/viewtopic.php?t=1433
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Gamma-linolenic acid (GLA) is the second fatty acid in the omega-6 family. It has 18 carbons and three double bonds (with the first double bond positioned six carbons from the end). The third fatty acid in the omega-6 family is dihomo-gamma-linolenic acid (DGLA) with 20 carbons and three double bonds. Next comes arachidonic acid (AA) with 20 carbons and 4 double bonds. The Series 1 prostaglandins are made out of DGLA and the Series 2 prostaglandins are made out of AA. Thus, GLA is an important transition product for the production of these prostaglandins.
GLA is found in small amounts in organ meats and in certain seed oils such as evening primrose oil, borage oil, and black currant oil. Hemp oil also contains GLA but this oil has no history of consumption by humans. The percentages of GLA in these specialty oils are as follows:
Evening Primrose Oil 10%
Black Currant Oil 17%
Borage Oil 23%
These three oils are available in capsule form. The body needs an enzyme called delta-6 desaturase (D6D) to transform linoleic acid into GLA. Under normal conditions, most people make adequate amounts of D6D and hence the by-product GLA; however, a number of disease and deficiency conditions as well as components of the modern diet can interfere with the conversion of linoleic acid to GLA. Diabetics, for example, do not normally make adequate amounts of D6D and hence of GLA, nor do people with poor pituitary or thyroid function. Both malnutrition and overeating can interfere with D6D and inhibit the production of GLA. Trans fatty acids definitely inhibit the production of GLA as does overconsumption of sugar and alcohol.
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http://www.westonaprice.org/knowyourfat ... lenic.html
Конопляное масло (К.м.), получаемое из плодов растения Cannabis sativa. К. м. обладает зеленоватым оттенком; в зависимости от способов получения может быть тёмным и светлым. К. м. содержит (%) 5,8-9,9 пальмитиновой, 1,7-5,6 стеариновой, 6-16 олеиновой, 36-50 линолевой, 15-28 линоленовой кислот. Йодное число 145-167. По химическому составу К. м. ближе других к льняному маслу и в ряде случаев может его заменить в производстве олиф, лаков и красок. Как пищевой продукт используется ограниченно.
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Мне идёт 39-й год, все фотографии уже в фотогалерее.Владислав писал(а):Могу предложить сделать фототрихограмму, цифровые фотографии и замеры скорости роста волос до лечения и повторить через 4 месяца от начала лечения. Хуже не будет, если нет сильной засаленности, а потому причины не попробовать -нет.